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More than 1 million sexually transmitted infections (STIs) are acquired every day worldwide. Sexually transmitted infections (STIs) are spread predominantly by unprotected sexual contact. Some STIs can also be transmitted during pregnancy, childbirth and breastfeeding and through infected blood or blood products. STIs have a profound impact on health. If untreated, they can lead to serious consequences including neurological and cardiovascular disease, infertility, ectopic pregnancy, stillbirths, and increased risk of Human Immunodeficiency Virus (HIV). They are also associated with stigma, domestic violence, and affects quality of life. The majority of STIs have no symptoms. When they are present common symptoms of STIs are vaginal or urethral discharge, genital ulcer and lower abdominal pain. The most common and curable STIs are trichomonas, chlamydia, gonorrhoea and syphilis. Rapidly increasing antimicrobial resistance is a growing threat for untreatable gonorrhoea. It is important that people from high- risk groups are regularly screened for infections and, on some occasions, may have more in-depth testing depending on the circumstances. Vaccinations against Hepatitis A, Hepatitis B and Human Papilloma virus (HPV) are available to those with increased risk.